Freshwater microalgae as messengers of biologically active substances in creation of new pharmacological groups of medicinal drugs

ІRSTІ 34.45.01                                                                                                 №4 (2018г.)

 

Ibragimova N.A., Lyu M.B., Mukhtarbekova I.S.

 

This study substantiates the development of new pharmacological groups of drugs based on microalgae with a unique complex of iodine adducts. The territory of the Republic of Kazakhstan is endemic for iodine deficiency, which is accompanied by chronic iodine insufficiency of the population, and therefore, the receipt of effective, safe and low-cost feed additives containing iodine adducts entering into the human body through the food chain with food is an actual one. On the other hand, the formation of resistance of bacterial strains to antibiotics leads to the resumption of development of iodine-based drugs with a broader activity and a lower probability of inducing microbial resistance. Microalgae are an ideal platform for the synthesis of new forms of effective drugs. Microalgae capable of bioaccumulating from trapped ions to form non-toxic compounds in the form of protein complexes, reducing the toxicity of the active substance of a potential biologically active substance.
Key words: iodine deficiency, bacterial resistance, microalgae, freshwater microalgae.

 

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